March 27, 2000 (Tampa, Fla.) — A unused consider suggests that taking vitamin C supplements may not be a good thought for cancer patients. In fact, researchers say, the vitamin may ensure tumors from the murdering impacts of radiation and chemotherapy.

The researchers, who displayed their discoveries at a meeting sponsored by the American Cancer Society, stop distant brief of suggesting that everybody maintain a strategic distance from vitamin C. In case a individual is healthy with no prove of cancer, there should be no stresses, says study creator David W. Golde, MD.

“Our suggestions are a healthy eat less of natural products and vegetables with tall intake of [dietary] vitamin C,” he says. “I don’t contend with anybody who takes vitamin supplementation. On the other hand, in a understanding with active cancer being treated with chemotherapy or radiation therapy, we think it’s prudent not to require high doses of vitamin C.”

Golde, who is physician-in-chief at Memorial Sloan-Kettering Cancer Center in Modern York, cautions that his team’s research, conducted in mice, does not demonstrate that vitamin C is hurtful. But, he says, it does suggest that a natural instrument exists that seem mean megadoses of the supplement would be harmful to certain people.

“That’s one thing we don’t often [know] about: the wholesome needs of the cancer itself … what it should grow, what it seems to need to assist its improvement,” says Golde, speaking at the American Cancer Society’s Science Writers’ Course here Monday.

Analysts do know that vitamin C is an antioxidant. It is taken up in large quantities by cells and can protect them from certain kinds of damage, called oxidative damage, that has been connected to heart disease and stroke. But radiation and chemotherapy depend on causing oxidative damage to destroy cancerous cells.

In their investigate, Golde and colleagues found that cancer cells take in more vitamin C than normal cells. They do this through a framework of transporters on their surfaces that pull expansive amounts of the vitamin into the cell, where it is stored or used to promote the cell’s functions, counting tumor development.

Hence, Golde says, high measurements of the vitamin may theoretically secure cancer cells from the exceptionally treatment meant to kill them. In spite of the fact that the ponder was done in mice, Golde says this might be translated to human cancers.

Restorative specialists at the assembly say that the findings highlight the significance of patients examining all use of supplements, counting vitamins and herbs, with their specialists — particularly in case they are experiencing treatment for cancer or other life-threatening illnesses.

“Elective treatments may keep patients from getting the care they require in a convenient design, ” says Barrie Cassileth, PhD, chief of the integrative medicine service, division of medicine, at Commemoration Sloan-Kettering Cancer Center.

At this point, Golde says, his study is preparatory. “Judicious exhortation is: exceptionally good nutrition for all individuals, counting cancer patients. But, when it comes to supplementation — taking exceptionally tall does of vitamin C — it’s sensible not to take it during [cancer] treatment,” he says.

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